Which enzyme catalyzes the breakdown of triglycerides?
Which enzyme is used to catalyze the hydrolysis of triglycerides quizlet?
Lipase catalyzes the hydration of carbon-carbon double bonds of fatty acyl CoA molecules. B). Lipase catalyzes the hydrolysis of ester bonds of triglycerides.
What type of enzyme catalyzes hydrolysis of triglycerides to glycerol and fatty acids?
What type of enzyme catalyzes hydrolysis reactions?
Which enzyme is important in the phase 2 reactions?
Phase 2 enzymes traditionally refer to the enzymes catalyzing the conjugation reactions, such as glutathione S-transferase (GST), UDP-glucuronosyltransferase ( UGT), N-acetyltransferase (NAT), and sulfotransferase (SULT).
Which of the following is a phase I reaction?
Phase I reactions are broadly grouped into three categories, oxidation, reduction, and hydrolysis. As most small molecule drugs are lipophilic in nature, drug metabolism converts these hydrophobic compounds into more water soluble compounds that can be excreted. Typically, oxidation is the most common phase I reaction.
Do intravenous drugs go through the liver?
A drug can be metabolized in the gut wall, but most commonly in the liver that is responsible for metabolism before the drug reaches the systemic circulation.
What is a high first pass effect?
Drugs with high first pass effect typically have a considerably higher oral dose than sublingual or parenteral dose. There is marked individual variation in the oral dose due to differences in the extent of first pass metabolism, frequently among several other factors.
What is meant by the first pass effect?
The first pass effect is a phenomenon in which a drug gets metabolized at a specific location in the body that results in a reduced concentration of the active drug upon reaching its site of action or the systemic circulation.
What are the 7 routes of medication administration?
- Oral route. Many drugs can be administered orally as liquids, capsules, tablets, or chewable tablets.
- Injection routes. Administration by injection (parenteral administration) includes the following routes:
- Sublingual and buccal routes.
- Rectal route.
- Vaginal route.
- Ocular route.
- Otic route.
- Nasal route.