What is the antidote of benzodiazepine?
Flumazenil is a selective competitive antagonist of the gamma-aminobutyric acid (GABA) receptor and is the only available specific antidote for benzodiazepine (BZD) toxicity; it will reverse the effects of BZDs but must be used with caution.
What is a major adverse side effect of barbiturate treatment for insomnia?
Common side effects include: Lightheadedness. Drowsiness. Confusion.
Which condition is a contraindication for barbiturates quizlet?
Which condition is a contraindication for barbiturates? Barbiturates can be used as hypnotics, sedatives, and anticonvulsants and for anesthesia. This class of drugs is contraindicated in patients with known drug allergy, pregnancy, or severe kidney or liver disease.
Which medication inhibits the pancreatic enzyme lipase?
Orlistat. A potent inhibitor of gastric and pancreatic lipase, orlistat (2) is a hydrogenated derivative of lipstatin, produced by Streptomyces toxytricini and acts by diminishing the absorption of dietary fat.
Which medication is contraindicated for a patient with narrow angle glaucoma who is having difficulty sleeping?
Benzodiazepines and topiramate contraindicated in acute narrow angle glaucoma patients.
Which drug should not be given with midazolam?
Shortly after you are treated with midazolam, using other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.
How long does it take versed to get out of your system?
The Versed half-life (or how long it takes for half of the drug to leave your system) averages out to about 3 hours. It is detectable via blood and urine drug tests and has a urine detection window of about one to two days.
Why does blood pressure drop when sedated?
Hypotension encountered during sedation is usually attributed to either vasovagal episodes or the use of sedative and anesthetic agents that depress sympathetic outflow to the cardiovascular system.
How does sedation affect heart rate?
Heart rate (HR) and arterial blood pressure (BP) changes have been reported during conscious sedation with propofol and midazolam. One potential mechanism to explain these changes is that propofol and midazolam affect HR and BP via changes in the cardiac autonomic nervous system.
Why is anesthesia bad for your heart?
The cardiovascular effects of general anesthesia include changes in the arterial and central venous pressures, cardiac output, and varying heart rhythms, which occur by the following mechanisms: decreased systemic vascular resistance, decreased myocardial contractility, decreased stroke volume, and increased myocardial …
Does sedation cause bradycardia?
Therefore, aggravated bradycardia can occur when spinal anesthesia and dexmedetomidine sedation are combined in a patient.
Can propofol cause tachycardia?
Data indicate that propofol can convert supraventricular tachycardia and ventricular tachycardia and may inhibit the conduction system of the heart. The mechanism of the cardiac effects remains poorly defined and may involve ion channels, the autonomic nervous system and cardiac gap junctions.
How long does it take for propofol to wear off?
The half-life of elimination of propofol has been estimated to be between 2 and 24 hours. However, its duration of clinical effect is much shorter, because propofol is rapidly distributed into peripheral tissues. When used for IV sedation, a single dose of propofol typically wears off within minutes.
Is Propofol bad for your heart?
PROPOFOL is now widely used in clinical practice because of its favorable recovery profile and low incidence of side effects. 1However, induction of anesthesia with propofol is often associated with a significant decrease in arterial blood pressure and heart rate (HR).