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2021-05-17

Why is the 3D structure of proteins so important in determining their function?

Why is the 3D structure of proteins so important in determining their function?

The shape of a protein is critical to its function because it determines whether the protein can interact with other molecules. Protein structures are very complex, and researchers have only very recently been able to easily and quickly determine the structure of complete proteins down to the atomic level.

Why does the structure of a protein determine its function?

Protein structure depends on its amino acid sequence and local, low-energy chemical bonds between atoms in both the polypeptide backbone and in amino acid side chains. Protein structure plays a key role in its function; if a protein loses its shape at any structural level, it may no longer be functional.

Why does myoglobin not have a quaternary structure?

Explanation: Quaternary structure of a protein involves the assembly of subunits. Hemoglobin, p53 and DNA polymerase are all composed of subunits, while myoglobin is a functional single sequence. Since myoglobin does not have multiple subunits, it does not have quaternary structure.

What is the highest level of protein structure in hemoglobin?

The quaternary structure of a hemoglobin molecule includes four tertiary structure protein chains, which are all alpha helices. Individually, each alpha helix is a secondary polypeptide structure made of amino acid chains. The amino acids are in turn the primary structure of hemoglobin.

Why does Haemoglobin not have disulfide bonds?

Most of the amino acids in hemoglobin form alpha helices, connected by short non-helical segments. (Hemoglobin has no beta strands and no disulfide bonds.) The backbone representation connects alpha carbon positions in this alpha helix. These lines do not represent the positions of any actual chemical bonds.

What are the two main components of Haemoglobin?

Hemoglobin is a protein formed of two subunits (alpha and beta) that is found in red blood cells. The protein functions to pick up oxygen and distribute it throughout the body.