Why is it important that DNA be replicated prior to cell division?
DNA replication needs to occur because existing cells divide to produce new cells. So the DNA needs to be copied before cell division so that each new cell receives a full set of instructions!
What would happen if DNA was replicated each time a new protein needed to be made?
If the DNA was replicated every time a protein is needed, the cell would have millions of DNA copies for no purpose at all, meaning a big waste of energy and space.
What are the three main steps in DNA replication?
Replication occurs in three major steps: the opening of the double helix and separation of the DNA strands, the priming of the template strand, and the assembly of the new DNA segment. During separation, the two strands of the DNA double helix uncoil at a specific location called the origin.
Which of the following enzymes is not required for DNA replication?
Which of the following proteins is not necessary during DNA replication? Explanation: RNA polymerase is an enzyme that transcribes RNA from DNA; it is not essential for DNA replication. This enzyme is easy to confuse with primase, whose primary function is to synthesize the RNA primers necessary for replication.
Is the leading strand 3 to 5?
Leading Strand and Lagging Strand The first one is called the leading strand. This is the parent strand of DNA which runs in the 3′ to 5′ direction toward the fork, and it’s able to be replicated continuously by DNA polymerase. The other strand is called the lagging strand.
What is lagging strand in DNA replication?
The lagging strand is the strand of new DNA whose direction of synthesis is opposite to the direction of the growing replication fork. Because of its orientation, replication of the lagging strand is more complicated as compared to that of the leading strand.
What is Primase in DNA replication?
Primase is an enzyme that synthesizes short RNA sequences called primers. Primase functions by synthesizing short RNA sequences that are complementary to a single-stranded piece of DNA, which serves as its template. It is critical that primers are synthesized by primase before DNA replication can occur.
What is difference between leading and lagging strand?
Within each fork, one DNA strand, called the leading strand, is replicated continuously in the same direction as the moving fork, while the other (lagging) strand is replicated in the opposite direction in the form of short Okazaki fragments.
What is the basis for the difference in the synthesis of the leading and lagging?
What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized? DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel.
Why do Okazaki fragments form during DNA replication quizlet?
What are Okazaki fragments? Why are they only formed on the lagging strand, not the leading strand? The segments of the lagging strand. The Okazaki fragments are formed because the lagging strands are made of the discontinued fragments.