Close

2021-05-14

What are some factors that can cause DNA mutations?

What are some factors that can cause DNA mutations?

Mutations arise spontaneously at low frequency owing to the chemical instability of purine and pyrimidine bases and to errors during DNA replication. Natural exposure of an organism to certain environmental factors, such as ultraviolet light and chemical carcinogens (e.g., aflatoxin B1), also can cause mutations.

What are 3 factors that cause mutations?

Mutations are caused by environmental factors known as mutagens. Types of mutagens include radiation, chemicals, and infectious agents. Mutations may be spontaneous in nature.

What are the two main types of causes of mutations?

Mutations, variations in the nucleotide sequence of a genome, can also occur because of damage to DNA. Such mutations may be of two types: induced or spontaneous. Induced mutations are those that result from an exposure to chemicals, UV rays, x-rays, or some other environmental agent.

Why is it significant that the four missense mutations are found?

Why is it significant that the missense mutations are found in the extracellular and intracellular domains of the protein? Changes in the structure of extracellular and intracellular portions can change the function of the protein in the signaling pathway or the transport mechanism.

What are substitution mutations?

‚ÄčSubstitution Substitution is a type of mutation where one base pair is replaced by a different base pair. The term also refers to the replacement of one amino acid in a protein with a different amino acid.

Which is an example of a transversion mutation?

Transversion substitution refers to a purine being replaced by a pyrimidine, or vice versa; for example, cytosine, a pyrimidine, is replaced by adenine, a purine.

What effects do mutations have?

When a mutation alters a protein that plays a critical role in the body, it can disrupt normal development or cause a medical condition. A condition caused by mutations in one or more genes is called a genetic disorder. In some cases, gene mutations are so severe that they prevent an embryo from surviving until birth.

Where do mutations occur?

Acquired (or somatic) mutations occur at some time during a person’s life and are present only in certain cells, not in every cell in the body. These changes can be caused by environmental factors such as ultraviolet radiation from the sun, or can occur if an error is made as DNA copies itself during cell division.

What is mutation and its types?

There are three types of DNA Mutations: base substitutions, deletions and insertions. 1. Base Substitutions. Single base substitutions are called point mutations, recall the point mutation Glu —–> Val which causes sickle-cell disease. Point mutations are the most common type of mutation and there are two types.

What is a visible mutation?

Visible mutation- Those mutation which affects on phenotypic character and can be detected by normal observation are known as visible mutation 2. Biochemical mutation- mutation which affect the production of biochemicals and which does not not show any phenotypic character are known as biochemical mutation.