Does raloxifene make you gain weight?
Raloxifene is associated with significantly less vaginal discharge and severe hot flashes than tamoxifen in women with early breast cancer. Although weight gain of >10 pounds may also occur less frequently on this drug, this may be confounded by the shorter average duration of raloxifene therapy.
Does raloxifene affect immune system?
Although raloxifene is known to have anti-inflammatory properties, its effects on human neutrophils, the primary phagocytic leukocytes of the immune system, remain poorly understood.
Does raloxifene cause joint pain?
Side effects may include hot flashes, leg cramps, swelling, flu-like symptoms, joint pain, and sweating.
Does raloxifene cause blood clots?
Because of its anti-estrogen effects, the most common side effects with raloxifene are hot flashes. Conversely, because of its estrogenic effects, raloxifene increases the risk of blood clots, including deep vein thrombosis (DVT) and pulmonary embolism (blood clots in the lung).
Does raloxifene cause weight loss?
Postmenopausal HT and raloxifene did not increase abdominal fat loss during weight loss, but did improve some cardiometabolic outcomes.
How long can you stay on raloxifene?
Background: Due to the chronic nature of osteoporosis and the risk of invasive breast cancer, raloxifene 60 mg/day (raloxifene) is intended to be used for long-term treatment (treatment >3 years).
Does Raloxifene raise cholesterol?
Raloxifene increased high-density lipoprotein-2 cholesterol (HDL2-C) by 15% to 17% (P<.
Can you stop taking raloxifene?
Remaining still for long periods may cause blood clots for some people, and raloxifene may rarely worsen their condition. If you are able to become pregnant, stop using the medicine immediately if you think you have become pregnant and check with your doctor.
Does raloxifene increase bone density?
Raloxifene is used to help prevent and treat thinning of the bones (osteoporosis) only in postmenopausal women. It works like an estrogen to stop the bone loss that can develop in women after menopause, but it does not increase the bone density as much as daily 0.625 mg doses of conjugated estrogens.
Does raloxifene cause dizziness?
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
What foods to avoid if you have osteoporosis?
Foods to limit or avoid
- High-salt foods. Excess salt consumption can cause your body to release calcium, which is harmful to your bones.
- Alcohol. While a moderate amount of alcohol is considered safe for those with osteoporosis, excess alcohol can lead to bone loss.
- Wheat bran.
- Excess vitamin A.
What is the life expectancy of a person with osteoporosis?
This excess risk is more pronounced in the first few years on treatment. The average life expectancy of osteoporosis patients is in excess of 15 years in women younger than 75 years and in men younger than 60 years, highlighting the importance of developing tools for long-term management.
Why do I need to see an endocrinologist for osteoporosis?
If your doctor has diagnosed you with osteoporosis or you’ve had fragility fractures of the spine or hip, you may be referred to an endocrinologist to confirm the diagnosis. Testing will be completed to look for other medical conditions that lead to bone loss, determine its severity, and select the best treatment.
What hormone is responsible for osteoporosis?
Parathyroid hormone (PTH) is an important contributor to the bone remodeling process. High levels of PTH can activate osteoclasts and cause excessive bone breakdown.
Do you need to see a specialist for osteoporosis?
If you have a primary care or family doctor, discuss your concerns with him or her. Your doctor may treat the disease or be able to refer you to an osteoporosis specialist. If you are enrolled in a health maintenance organization (HMO) or a managed care health plan, consult your assigned doctor about osteoporosis.
How can I increase my bone density after 60?
5 Ways to Strengthen Older Bones
- Exercise. Just 30 minutes of exercise each day can help strengthen bones and prevent osteoporosis.
- Eat a balanced diet.
- Take supplements.
- Make sure your body absorbs the calcium and vitamin D it needs.
- Avoid salty foods and caffeinated beverages.
- Get a bone density scan.