IRCCS San Raffaele Pisana

The SRS Pisana Scientific Institute for Research, Hospitalization and Health Care (IRCCS in the Italian acronym) is accredited by the Italian National Health Service and represents the core of all clinical facilities of the San Raffaele Network (34 hospitals) spread over the national territory (overall 2800 beds circa). The longstanding tradition and mission of SRS Institute is rehabilitation in different areas (Neurology, Cardiology, Pneumology, ENT, Orthopedics, Pediatrics). As of 2003 a tele‐medicine/tele‐ rehabilitation service has been implemented to a) support peripheral hospitals of the network with tele‐ diagnosis and second opinions and b) provide home tele‐monitoring and tele‐rehabilitation programs. The Research Centre includes common facilities and the following laboratories for translational research: Advanced and Integrated Functional Neuroimaging, Clinical Neuro‐Physiology, and Neurosonology, Molecular and Cellular Neurobiology, Cellular and Molecular Pathology, Cellular Neurophysiology, Vascular Endocrinology, Cellular and Molecular Immunology, Biochemistry of Ageing, Human Nutrition, Molecular Biology and Proteomics. Also a Department of Clinical and Molecular Epidemiology supports the research activity. The research of the Department of Neurorehabilitation is focused on functional recovery, on the prevention of stroke recurrence, and on treatment of cardiovascular co‐morbidities. The activities of the Neurorehabilitation Department are focused on the following major clinical topics:

1) Upper Limb Neuro‐Rehabilitation using Robotic systems in post‐acute stroke patients;

2) Upper Limb Neuro‐Rehabilitation with action‐observation task in chronic stroke patients;

3) Longitudinal observational studies in Stroke patients in Italy with basic common rehabilitative protocols and recovery assessments;

4) Welfare and Social costs/burden in post‐stroke disabled patients;

5) Innovative approaches to favour rapid re‐introduction into working activities of disabled post‐stroke patients, with special interest on physiopathology of brain hemodynamic;

6) Analysis of the role of functional neuro‐imaging in brain re‐organization;

7) Neuroprosthetics and Robotics.

Role in SCRIPT:
1. Clinical validation
2. End‐user requirements
3. Overall implementation of the SCRIPT platform into clinical management

Expertise in SCRIPT:
IRCCS San Raffaele (SRS) is contributing to the project by providing its knowledge and experience on Clinical Neurology, Neurophysiology, Neuro‐Rehabilitation, and Bioengineering, Epidemiology and Bio‐Statistics. SRS will as well actively participate in the overall management, dissemination and exploitation activities of the project. The focus of SRS participation in this project lies on tele‐rehabilitation requirements identification, patient management, treatment and evaluation, epidemiological support to the study and bio‐statistical data management. SRS will, as well, provide support for the project's liaison activities with the European Commission services.